Yuanyuan
GUO

PROJECT

Microelectronic fiber-based multiplexed neurochemical sensors


Worldwide, billions of individuals suffer from various brain disorders. Search for effective therapeutic strategies requires the mechanistic understanding of the functional neural circuits involved from the molecular, cell, circuit, and system levels to behavioral levels. Such endeavor ultimately relies on engineering innovations to establish an interface that matches this multi-level complexity. The critical issue in the current neural interface resides in insufficient capabilities to investigate in-brain chemistry dynamically with high chemical, temporal, and spatial resolutions. The central objective of this proposal is to approach these attributes by designing and developing a flexible nano-/microelectronic fiber-based neural interface for multiplexed neural chemical sensing and imaging.
 

BIOGRAPHY